Pain Killer Drug Fenacetina CAS 62-44-2 Local Anesthetic
Description of Phenacetin
Phenacetin is a synthetic, white crystalline solid that is slightly
soluble in water and benzene, soluble in acetone and very soluble
in pyrimidine. It is used in research as the preferred marker for
detecting CYP1A2-based inhibition potential in vitro. Human
ingestion of phenacetin can result in a bluish discoloration of the
skin due to a lack of oxygen in the blood (cyanosis), dizziness and
respiratory depression. It is reasonably anticipated to be a human
English Synonyms: 1-acetamido-4-ethoxybenzene;
p-acetophenetide; p-acetphenetidin; paracetophentidin;
Para-phenaceti; acet-p-phenalide; acet- p-phenetidin;
aceto-para-phenalide; aceto-para-phenetidide; Acetophenetidine;
acetophenetin; acetylphenetidin; coricidin; empirin compound;
N- (4-ethoxyphenyl) -acetamide; N-Acetyl-4-ethoxyaniline;
N-acetyl-p -phenetidine; phenacet; phenacitin; phenazetin;
Molecular Formula: C10H13NO2
Molecular Weight: 179.24
Density: 1.099 g/cm3
Melting Point: 133-136 C(lit. )
Boiling Point: 355.1 C at 760 mmHg
Flash Point: 168.5 C
Solubility: 0.076 g/100 mL in water
Appearance: White crystalline powder
Packing: Foil bag or as required
Uses: Antipyretic analgesics for the treatment of fever, headache,
Fuction of Phenacetin
1)Used for organic synthesis of raw materials and drug
intermediates from acetaminophen ether.
2)Antipyretic analgesics for the treatment of fever, headache,
3)Active pharmaceutical ingredient for Scientific Research.
Analgesic mixtures containing phenacetin were previously marketed
as tablets or capsules containing between 150 and 300 mg
phenacetin. Common combinations were: 150 mg phenacetin, 230 mg
aspirin, and 15 or 30 mg caffeine; or 150 mg phenacetin, 230 mg
aspirin, 30 mg caffeine, and 8, 15, 30, or 60 mg codeine phosphate.
Phenacetin alone was also available in 250 and 300 mg doses as
tablets, and up to 500 mg doses as powder. The usual dose was 300
mg 4-6 times per day, and the daily dose was not to exceed 2 g.
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